Rapid versus slow feed advancement in babies who did not cry at birth

Rapid vs slow advancement of early enteral nutrition in neonates with perinatal asphyxia on therapeutic hypothermia: a randomized controlled trial-non inferiority trial - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/01/061507

Enrollment

Registered

2024-01-16

Start date

Unknown

Completion date

Unknown

Last updated

2024-01-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical Health Condition 2: P039- Newborn affected by complication of labor and delivery, unspecified

Interventions

Intervention1: Rapid advancement of enteral feeds: feeds will be advanced at the rate of 30ml/Kg/day for 3 days and then advance to full feeds on day 4. Control Intervention1: Slow advancement of en

Eligibility

Inclusion criteria

Inclusion criteria: All babies with GA > 35 weeks with moderate to severe hypoxic ischemic encephalopathy requiring Therapeutic hypothermia .

Exclusion criteria

Exclusion criteria: Nil

Design outcomes

Primary

Measure	Time frame
: To assess composite outcome of feed intolerance and or mortality in term infants with HIE on THTimepoint: 4 weeks and 8 weeks	—

Secondary

Measure	Time frame
time to reach full enteral feeds: a feed volume of 140ml/kg/day, length of NICU stay, incidence of feed intolerance, incidence of sepsisTimepoint: 28 days	—

Countries

India

Contacts

Public ContactAbhilasha Gupta

Seth GS Medical College and KEM Hospital

ani.gem81@gmail.com09769660870

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026