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A comparative study of efficacy of preoperative Dexmedotimidine nebulization with Magnesium sulphate nebulization in reducing post operative sore throat in patients undergoing general anaesthesia

A comparative study of efficacy of preoperative Dexmedotimidine nebulization with Magnesium sulphate nebulization in reducing post operative sore throat in patients undergoing general anaesthesia - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2024/01/061491
Enrollment
60
Registered
2024-01-15
Start date
Unknown
Completion date
Unknown
Last updated
2024-01-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: R098- Other specified symptoms and signsinvolving the circulatory and respiratory systems

Interventions

Intervention1: Group D: Dexmeditomidine 1mcg/kg body weight in 4 ml normal saline for 15 min Intervention2: Group M: Magnesium Sulphate 250 mg in 4 ml normal saline for 15 min Control Intervention1: G

Sponsors

Department of Anaesthesiology
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: All ASA grade I and grade II patients between 19 to 60 years of age group of both sexes Mallampati grade 1 and 2 duration of surgery less than 2 hours Body mass index 25 to 30 kg/m2 Elective surgeries under general anasesthesia with endotracheal intubation and controlled ventilation

Exclusion criteria

Exclusion criteria: Age 60 years ALL ASA Grade III and above Mallampati grade III and above Patients with URTI, LRTI, Asthma, COPD, Smoking Difficult airway, who need nasogastric tube insertion. Head and Neck surgeries, Emergency surgeries Patients who require more than one attempt of intubation and in whom the time taken for intubation is more than 20s

Design outcomes

Primary

MeasureTime frame
Post Operative Sore Throat Present or Absent If present Grade 0 to 3Timepoint: 24 hours

Secondary

MeasureTime frame
Adverse effects likenausea, vomiting, dry mouth, sedationTimepoint: 0hr, 2hr, 6hr, 12hr, 24hrs

Countries

India

Contacts

Public ContactSindhu N Pawadigoudra

Mysore medical college and research institute

sindhunp1@gmail.com8150802056

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026