comparison of pain duration between dexmedtomidine and dexamathasone along with ropivacaine in ultrasound guided adductor canal block among patients undergoing unilateral total knee replacement

Comparison of Pain Relief Between Dexmedetomidine and Dexamethasone as Adjuvants to Ropivacaine in Ultrasound Guided Adductor Canal Block in Unilateral Total Knee Replacement. - nil

Status

Active, not recruiting

Phases

Phase 4

Study type

Observational

Source

CTRI

Registry ID

CTRI/2024/01/061472

Enrollment

100

Registered

2024-01-15

Start date

Unknown

Completion date

Unknown

Last updated

2024-01-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: I10- Essential (primary) hypertension Health Condition 2: E011- Iodine-deficiency related multinodular (endemic) goiter Health Condition 3: E119- Type 2 diabetes mellitus without complications

Interventions

Intervention1: ADDUCTOR CANAL BLOCK IN UNILATERAL TKR -DEXMEDETOMIDINE 50MCG, DEXAMETHASONE 4 MG: DEXAMETHASONE 4MG VERSUS DEXMEDETOMIDINE 50MCG AS ADJUVANT TO 0.2% 20ML ROPIVACAINE IN ADDUCTOR CANAL

Eligibility

Inclusion criteria

Inclusion criteria: 1)Patients posted for elective unilateral TKR under Subarachnoid block 2)ASA 1,11 grade of patients 3)Age group above 40 years

Exclusion criteria

Exclusion criteria: 1) Patients refusal 2) Duration of surgery more than 2 hours 3)Patients with uncontrolled psychiatric illness 4)Patients with known allergy to local anaesthetics ,Morphine, Fentanyl or Paracetamol. 5) Patients with peripheral neuropathy 6) Patients with known absolute contraindications to regional anaesthesi

Design outcomes

Primary

Measure	Time frame
1) To compare the duration of post-operative analgesia between Dexmedetomidine and Dexamethasone as adjuvants to 0.2% Ropivacaine in Adductor Canal Block among patients undergoing unilateral TKR . Timepoint: 24HOURS	—

Secondary

Measure	Time frame
Following postoperative Adductor Canal Block in Unilateral TKR. 1) To compare postoperative pain at rest and during mobilisation of knee joint between the two groups. 2) To compare the quality of sleep between the two groups. 3) To compare the sedation sedation scores between the two groups. 4) To compare the adverse effects like nausea, and vomiting, hemodynamic instability between two groups. Timepoint: 24HOURS	—

Measure

Time frame

Following postoperative Adductor Canal Block in Unilateral TKR. 1) To compare postoperative pain at rest and during mobilisation of knee joint between the two groups. 2) To compare the quality of sleep between the two groups. 3) To compare the sedation sedation scores between the two groups. 4) To compare the adverse effects like nausea, and vomiting, hemodynamic instability between two groups. Timepoint: 24HOURS

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Countries

India

Contacts

Public ContactDr Fidha.A

believers church medical college hospital

drabbeymathew@gmail.com9843036269

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026