Health Condition 1: D25- Leiomyoma of uterus
Conditions
Interventions
Intervention1: Mifepristone: Tab Mifepristone 25mg once daily for 3 months
Control Intervention1: Tab Tranexamic acid, Tab Mefenamic acid: Tab Tranexamic acid and Tab Mefenamic acid thrice daily durin
Sponsors
Silchar Medical College and Hospital
Eligibility
Inclusion criteria
Inclusion criteria: Women of reproductive age group (18-49 years) with 1. All symptomatic fibroids of different sizes and anatomical positions but less than 12 weeks size. 2. All asymptomatic fibroids of size 2.5cm or more detected on ultrasonography done for evaluation of other complaints but less than 12 weeks size. 3. Asymptomatic multiple fibroids of size less than 2.5 cm detected on sonography done for evaluation of other complaints but less than 12 weeks size.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To compare the mean PBAC scores between mifepristone and tranexamic acid, mefenamic acid in the management of uterine fibroids. - To compare the mean Numeric Pain Scale Rating scores for dysmenorrhea and intermenstrual abdominal pain between the two groups. - To compare the changes in uterine volume, fibroid dimension, and endometrial thickness between the two groups. - To compare the effect on hemoglobin levels between the two groups. Timepoint: 1 year | — |
Secondary
| Measure | Time frame |
|---|---|
| To assess the need for surgery or change of therapy between the two groups Timepoint: 1 year | — |
Countries
India
Contacts
Public ContactPiyalee Nath
Silchar Medical College and Hospital
Outcome results
None listed