Health Condition 1: L400- Psoriasis vulgaris
Conditions
Interventions
Intervention1: Methotrexate Gel (1%): Folate antagonist, Dose - 1%, Frequency - Twice daily, Route - Topical application over lesions, Follow up - 2 weeks, 4 weeks, 6 weeks, 8 weeks, Duration of study
Sponsors
Eras Lucknow Medical College and Hospital
Eligibility
Inclusion criteria
Inclusion criteria: Psoriasis vulgaris patients with less than 10% of body surface area involvement attending dermatology OPD at Eras Lucknow Medical College and Hospital
Exclusion criteria
Exclusion criteria: 1. Patients of psoriasis on topical, systemic, intralesional therapy or phototherapy for atleast 6 months prior to study 2. Patients having hypersensitivity to methotrexate or calcipotriol 3. Pregnant and lactating females
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To compare the therapeutic response of methotrexate gel (1%) with calcipotriol ointment (0.005%) in patients of psoriasis vulgarisTimepoint: 0,2,4,6,8 weeks | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. To study the efficacy of methotrexate gel (1%) in psoriasis vulgaris 2. To study the efficacy of calcipotriol ointment (0.005%) in psoriasis vulgaris 3.To identify any adverse effects associated with the use of methotrexate gel (1%) and calcipotriol ointment (0.005%) in the treatment of psoriasis vulgarisTimepoint: 0,2,4,6,8 weeks | — |
Countries
India
Contacts
Public ContactBhavika Bansal
Eras Lucknow Medical College and Hospital
Outcome results
None listed