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Efficacy of different flow rates for delivering oxygen via HHFNC in children with bronchiolitis.

Comparison of 3 different flow rates of High Flow Nasal Cannula (1litre/kg/min versus 2litre/kg/min versus 3litre/kg/min) in management of children admitted with bronchiolitis: A Randomized Controlled Trial.

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/01/061430
Enrollment
90
Registered
2024-01-12
Start date
Unknown
Completion date
Unknown
Last updated
2024-01-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: J20-J22- Other acute lower respiratory infections

Interventions

Intervention1: Comparison of 3 different flow rates of High Flow Nasal Cannula (1litre/kg/min versus 2litre/kg/min versus 3litre/kg/min) in management of children admitted with bronchiolitis: A Random

Sponsors

Non sponsored study
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Children aged 1 month to 1 year diagnosed with acute bronchiolitis diagnosed clinically as per American academy of paediatric guidelines and classified into mild , moderate and severe bronchiolitis based on Clinical Respiratory Score.

Exclusion criteria

Exclusion criteria: Clinically ill infants who need immediate respiratory support and ICU admission. Infants with previously diagnosed congenital heart disease, neurological disorders. Infants with upper airway obstruction. Infants with craniofacial malformations. Infants who have received oxygen therapy at home or other hospital. Infants having coexisting pneumothorax or nasal trauma. Infants whose parents refuse to give consent to participate in study.

Design outcomes

Primary

MeasureTime frame
To assess the clinical response of oxygen therapy via HHFNC @ 1litre/kg/min versus 2litre/kg/min versus 3litre/kg/min. Need of invasive ventilation Need of ICU admissionTimepoint: 48 hours

Secondary

MeasureTime frame
Therapy failure Icu transfer Intubation Reduction in respiratory rate Reduction in heart rate Rise in spo2Timepoint: 48 hours

Countries

India

Contacts

Public ContactManju

PGIMS ROHTAK

drkapilbhalla@gmail.com9813743565

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026