Health Condition 1: 3- Administration
Conditions
Interventions
Intervention1: Drug administration: Intralesional injections of Placentrex in group 2, Hyaluronidase and dexamethasone in group 3, and Combination of Placentrex, Hyaluronidase, and dexamethasone in gr
Sponsors
Jay Goyal
Eligibility
Inclusion criteria
Inclusion criteria: The patients diagnosed with Grade 2, and Grade 3 of oral submucous fibrosis (OSMF), as evident from their detailed clinical and histopathological examination
Exclusion criteria
Exclusion criteria: The patients with previous treatment of OSMF, patients who had Grade 1 and 4 OSMF, who were allergic to placental extract, steroids, and hyaluronidase, the patients who did not give their consents, who have syndromic or systemic disease with mouth ulcers, who had undergone radiotherapy sessions leading to oral ulcers, those who gave previous history of major surgery in the oral cavity, patients with carcinoma of oral cavity, were excluded from the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The significant increase in the mouth-opening and relief of burning sensation with combination intralesional injection therapy in OSMFTimepoint: at Baseline, 4th week, 8th week, 12th week and 12th month. | — |
Secondary
| Measure | Time frame |
|---|---|
| The significant increase in the mouth-opening and relief of burning sensation with combination intralesional injection therapy in OSMFTimepoint: At baseline | — |
Countries
India
Contacts
Public ContactJay Goyal
Jawahar Medical Foundations Aannasaheb Chudaman Patil Memorial Dental College
Outcome results
None listed