Health Condition 1: P590- Neonatal jaundice associated withpreterm delivery
Conditions
Interventions
Intervention1: EXTRA FLUID THERAPY: Received extra fluid volume- one fourth of maintenance fluid (maximum: 30 ml/kg/day) either 5% dextrose at 24-48h or N/5 5% dextrose after 48h over 12-hour intra ve
Sponsors
Aradhana
Eligibility
Inclusion criteria
Inclusion criteria: Preterm neonate (29-33 +6) with severe unconjugated hyperbilirubinemia during first two weeks of life.
Exclusion criteria
Exclusion criteria: Jaundice 40%, symptomatic PDA or CHD, neonatal encephalopathy, TSB level above 5mg/dl of exchange transfusion threshold
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Compare the decline in serum bilirubin level at 6 hourly,18 hourly & then every 12 hourly in both groups.Timepoint: 6th hourly, 18th hourly and then every 12th hourly till S. Bilirubin is below cut off for phototherapy. | — |
Secondary
| Measure | Time frame |
|---|---|
| Compare the need of exchange transfusion, bilirubin induced encephalopathy & possible clinical effect of extra fluid supplementation such as, weight gain, increased oxygen requirement, derangement in serum sodium level, need of extra intravenous line, opening of Patent ductus arteriosus in both arms.Timepoint: 4 hours after starting phototherapy | — |
Countries
India
Contacts
Public ContactAradhana
KALINGA INSTITUTE OF MEDICAL SCIENCES
Outcome results
None listed