Efficacy of detecting orthodontic root resorption

Efficacy of detecting orthodontic root resorption using Dentin Sialophosphoprotein (DSPP) biomarker in gingival crevicular fluid (GCF) of premolars subjected to orthodontic intrusive forces - A controlled clinical trial - NIL

Status

Active, not recruiting

Phases

Phase 2Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/01/061380

Enrollment

Registered

2024-01-11

Start date

Unknown

Completion date

Unknown

Last updated

2024-01-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K033- Pathological resorption of teeth

Interventions

Intervention1: Orthodontic intrusion: Orthodontic intrusive forces given on premolars for a period of 12 weeks Control Intervention1: No orthodontic treatment: No orthodontic intrusive forces were giv

Eligibility

Inclusion criteria

Inclusion criteria: Adult subjects aged 18 to 30 years with no congenital anomalies, systemic diseases, missing teeth, or a history of previous orthodontic treatment requiring malocclusion correction.

Exclusion criteria

Exclusion criteria: Subjects below the age group of 18 years and above the age group of 30 years, with congenital anomalies, systemic diseases, missing teeth, or a history of previous orthodontic treatment.

Design outcomes

Primary

Measure	Time frame
To evaluate changes in the Dentin Sialophosphoprotein biomarker levels between study & control groupsTimepoint: For a period of 12 weeks	—

Secondary

Measure	Time frame
To evaluate root resorption craters before & after orthodontic intrusive forces. Timepoint: 12 weeks	—

Countries

India

Contacts

Public ContactAshwin Mathew George

Saveetha Dental College and Hospital

ashwingeorge90@yahoo.com9840032771

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026