Health Condition 1: K800- Calculus of gallbladder with acutecholecystitis Health Condition 2: K802- Calculus of gallbladder without cholecystitis
Conditions
Interventions
Intervention1: Administration of two diiferent doses of dexmedetomidine intervenously: preoperative administration of two different doses intravenous dexmedetomidine for patients undergoing laparoscop
Sponsors
Department of Anaesthesia and Intensive Care
Eligibility
Inclusion criteria
Inclusion criteria: 1. ASA physical status I and II of either sex 2. Age between 18 to 65 years 3. BMI =20 to=35 kg m2 4. Scheduled for laparoscopic cholecystectomy surgery
Exclusion criteria
Exclusion criteria: 1. Refusal by the patient 2. Patient with coagulopathy and bleeding disorder 3. Pregnant or lactating women 4. Contraindications or allergy to dexmedetomidine and fentanyl 5. Patient having hemodynamic instability. 6. Patients having pain in any area other than surgery site
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Total intraoperative rescue dose of fentanyl consumed.Timepoint: 0, 5, 15mins before induction, at the time of intubation and every 10 minutes after intubation till the end of surgery | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Haemodynamic response at 0, 5, 15mins before induction, at the time of intubation and every 10 minutes after intubation till the end of surgery. 2. Total induction dose of propofol consumed. 3. Post-operative VAS score at patient arrival at PACU, 5, 10, 15, 30 minutes 1, 3, 6, 12 and 24 hours. 4. Time to first rescue analgesia postoperatively. 5. Adverse effects if any. Timepoint: 0 minutes, 5 minutes, 10 minutes, 15 minutes, 30 minutes, 1 hour, 3 hours, 6 hours, 12 hours, 24 hours | — |
Countries
India
Contacts
Public ContactDr Deepak Thapa
Government Medical College and Hospital
Outcome results
None listed