Prophylactic Mirtazepine Tablet 30mg and Ondansetron 4mg in lower abdominal surgeries

Prophylactic Mirtazepine and Ondansetron for the prevention of post spinal anaesthesia shivering in lower abdominal surgeries: A Randomized clinical study - Nil

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/01/061266

Enrollment

Registered

2024-01-09

Start date

Unknown

Completion date

Unknown

Last updated

2024-01-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: R00-R99- Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified

Interventions

Intervention1: Tablet Mirtazepine 30mg: Study participants will be Randomized into 2 groups. Group M will receive Tablet Mirtazepine 30mg 2hrs before surgery. Control Intervention1: Tablet Ondansetron

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patients undergoing elective lower abdominal surgeries 2. Age 18 to 60 years of either sex 3. Treatment with sedative hypnotics

Exclusion criteria

Exclusion criteria: 1. Patients with history of allergy to drug 2. Diabetes Mellitus, thyroid diseases, cardiopulmonary disease, psychological disorder, neurological deficit, liver diseases 3. Treatment with sedative hypnotics 4. Body temperature 38 degree Celsius 5. Local site infection 6. Spinal deformity 7. Bleeding tendencies- platelet count 14sec, INR >1.5

Design outcomes

Primary

Measure	Time frame
Post spinal anaesthesia shiveringTimepoint: Outcome will be assessed during the intraoperative period.	—

Secondary

Measure	Time frame
NilTimepoint: Nil	—

Countries

India

Contacts

Public ContactLongjam Eshori

Regional Institute of Medical science Imphal

drlongjam@gmail.com9436036407

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026