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Neonatal and placental genetic studies to find out the causes of intrauterine growth retardation

Study of Placental and neonatal gene signatures responsible for intrauterine growth retardation and insulin resistance during childhood - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2024/01/061243
Enrollment
75
Registered
2024-01-08
Start date
Unknown
Completion date
Unknown
Last updated
2024-01-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O289- Unspecified abnormal findings on antenatal screening of mother

Interventions

Intervention1: nil: nil

Sponsors

ICMR,New Delhi
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.IUGR neonates diagnosed during pregnancies by antenatal ultrasound as abdominal Circumference 2. Mothers of these IUGR neonates

Exclusion criteria

Exclusion criteria: i. Multiple births ii. Proven Intrauterine infection iii. Major malformations iv. Maternal chronic diseases v. Identifiable syndromic neonate

Design outcomes

Primary

MeasureTime frame
1.Abnormalities in placental and neonatal microarray, 2.Abnormal placental histopathology in idiopathic IUGR. 3. 5.Comparison with placentae from PE and healthy control mothers Timepoint: 18 months—

Secondary

MeasureTime frame
Maternal VEGF , PlGF and cord IGF1 and their correlations with birth weight and growth at 18 months. 4. Abnormal insulin polymorphisms at birth and insulin resistance at 18 monthsTimepoint: 18 months—

Countries

India

Contacts

Public ContactKanya Mukhopadhyay

PGIMER,Chandigarh

kanyapgi@gmail.com9914208317

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026