Health Condition 1: G988- Other disorders of nervous system
Conditions
Interventions
Intervention1: REPITITIVE TRANSCRANIAL MAGNETIC STIMULATION: The treatment arm will consist of 3 consecutive daily
treatment sessions.
One treatment session in this study with real
rTMS will consist o
Sponsors
AIIMS Bhubaneswar
Eligibility
Inclusion criteria
Inclusion criteria: 1. First-time stroke 2. Stroke with in 7 to 30days 3. 18 years of age or older 4. Gender- either male or female 5. Ability to follow three-step directions 6. patients with no spasticity or minimal spasticity 7. Sufficient ambulation or wheelchair mobility to allow subject to present to treatment and testing areas with minimum assist
Exclusion criteria
Exclusion criteria: 1. History of seizure within the past two years 2. Inability to follow three-step directions 3. Anosognosia 4. Moderate to severe receptive aphasia 5. Premorbid spasticity or neurologic impairment prior to stroke 6. Co-morbidities impairing upper extremity function such as fracture or deformity 7. Indwelling metal or medical devices incompatible with TMS 8. Pregnancy 9. Bi-hemispheric or multifocal stroke 10. Severe dementia 11. Neurolytic injection within the 3 months prior to onset of study or planned neurolytic injection during study period
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Change in Baseline modified Modified Ashworth Scale score from Day 1 (Pre-treatment) to Day 5 (Post-treatment),at 1monthTimepoint: Change in modified Modified Ashworth Scale score at baseline,at 4weeks and 12weeks. | — |
Secondary
| Measure | Time frame |
|---|---|
| 1.Motor function improvement will be assessed through digital hand dynamometer. 2.Change in Baseline Corticospinal Excitability Measures from Day 1 (Pre-treatment) to Day 5 (Post- treatment). Corticospinal excitability measures used will include threshold & motor evoked potential (MEP) amplitude & cortical silent period duration.Timepoint: at baseline,4weeks & at 12weeks | — |
Countries
India
Contacts
Public ContactDr sanjeev kumar Bhoi
AIIMS BHUBANESWAR
Outcome results
None listed