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Study to determine the incidence of hyperchloremia and its complication among ICU patients.

A cross sectional study to determine the incidence of hyperchloremia in sepsis and its associated complication among critical patients admitted to ICUs of selected tertiary care hospital, Udupi district. - Nil

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2024/01/061201
Enrollment
510
Registered
2024-01-08
Start date
Unknown
Completion date
Unknown
Last updated
2024-01-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: N179- Acute kidney failure, unspecified Health Condition 2: E878- Other disorders of electrolyte andfluid balance, not elsewhere classified

Interventions

Control Intervention1: Nil: Nil

Sponsors

Mr Kallesh R
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: The Patients 18 to 80 years of age. Duration of stay in the ICU 24 hours to 72 hours. Patients with sepsis condition with SOFA =2 or APACHE II.

Exclusion criteria

Exclusion criteria: Patients with symptoms like upper gastrointestinal bleeding, melaena, hematuria, petechiae, or skin lesions that may have hematomas. Individuals with chronic kidney disease. Patient admitted with acute renal damage according to RIFLE criteria. patients undergoing peritoneal dialysis or hemodialysis. Patients taking acetazolamide, methazolamide, dorzolamide, or ethoxzolamide, or any other carbonic anhydrase inhibitor. Chloride on admission greater than one hundred and six mmol per litter

Design outcomes

Primary

MeasureTime frame
hyperchloremia, hemoglobin, white blood cell count, platelet, urea, creatinine, prothrombin time, INR, Arterial blood gas values (pH, PaO2, PaCO2, HCO3, lactate, base deficit, anion gap), neutrophil lymphocyte ratio, APACHE II score, SOFA score, days of ICU stay, days of ventilator stay, renal replacement therapy, mortality, Procalcitonin, c-reactive protein.Timepoint: 24 hours and 72 hours

Secondary

MeasureTime frame
Prolonged ICU stay more than fourteen days.Timepoint: More than 14 days

Countries

India

Contacts

Public ContactDr Melita Sheilini

Manipal College of Nursing, MAHE Manipal

soumya.christabel@manipal.edu9739319382

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026