Health Condition 1: N179- Acute kidney failure, unspecified Health Condition 2: E878- Other disorders of electrolyte andfluid balance, not elsewhere classified
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: The Patients 18 to 80 years of age. Duration of stay in the ICU 24 hours to 72 hours. Patients with sepsis condition with SOFA =2 or APACHE II.
Exclusion criteria
Exclusion criteria: Patients with symptoms like upper gastrointestinal bleeding, melaena, hematuria, petechiae, or skin lesions that may have hematomas. Individuals with chronic kidney disease. Patient admitted with acute renal damage according to RIFLE criteria. patients undergoing peritoneal dialysis or hemodialysis. Patients taking acetazolamide, methazolamide, dorzolamide, or ethoxzolamide, or any other carbonic anhydrase inhibitor. Chloride on admission greater than one hundred and six mmol per litter
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| hyperchloremia, hemoglobin, white blood cell count, platelet, urea, creatinine, prothrombin time, INR, Arterial blood gas values (pH, PaO2, PaCO2, HCO3, lactate, base deficit, anion gap), neutrophil lymphocyte ratio, APACHE II score, SOFA score, days of ICU stay, days of ventilator stay, renal replacement therapy, mortality, Procalcitonin, c-reactive protein.Timepoint: 24 hours and 72 hours | — |
Secondary
| Measure | Time frame |
|---|---|
| Prolonged ICU stay more than fourteen days.Timepoint: More than 14 days | — |
Countries
India
Contacts
Manipal College of Nursing, MAHE Manipal