Comparison of dexmedetomidine and clonidine in caudal block in paediatric patients posted for infra umbilical surgeries.

Comparative study to evaluate efficacy and safety of dexmeditomidine and clonidine as adjuvant with bupivacaine for caudal block in pediatric patients posted for infra umbilical surgeries. - NIL

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/01/061191

Enrollment

Registered

2024-01-08

Start date

Unknown

Completion date

Unknown

Last updated

2024-01-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: N399- Disorder of urinary system, unspecified

Interventions

Intervention1: Dexmedetomidine: 1 microgram/kg Dexmedetomidine as adjuvant to 0.25% of 1 ml /kg of bupivacaine approximate duration of procedure is 2 to 3 minutes. Control Intervention1: Clonidine: 1

Eligibility

Inclusion criteria

Inclusion criteria: 1. Pediatric patients from 2 yrs to 6 years. 2. ASA grade I-II 3. Pediatric patients undergoing infraumbilical surgeries like hernia repair, circumcisions, orchidopexy, etc.

Exclusion criteria

Exclusion criteria: 1.Children less than 2 yrs or more than 6 yrs. 2.ASA grade III –IV. 3.Known allergy to any of the study drugs. 4.Pre-operative hepatic or renal dysfunction. 5.Serious cardiac or respiratory disease. 6.History of developmental delay or mental retardation. 7.Known or suspected coagulopathy. 8.Signs of infection at the site of the proposed caudal block.

Design outcomes

Primary

Measure	Time frame
To compare caudal epidural bupivacaine with clonidine & bupivacaine with dexmedetomidine regarding the duration of analgesia in pediatric patients posted for infraumbilical surgeries under general anesthesiaTimepoint: 12 hours	—

Secondary

Measure	Time frame
To assess the synergistic effect & safety of adding dexmedetomidine to bupivacaine compared with clonidine to bupivacaine in caudal block in infraumbilical surgeries. To compare the haemodynamic changes during intraoperative and postoperative period. To compare the quality and duration of postoperative analgesia. To compare the total amount of rescue analgesics used during the 12 hour post operative period. To study the side effects and complications during the post operative period. Timepoint: 12 hours	—

Measure

Time frame

To assess the synergistic effect & safety of adding dexmedetomidine to bupivacaine compared with clonidine to bupivacaine in caudal block in infraumbilical surgeries. To compare the haemodynamic changes during intraoperative and postoperative period. To compare the quality and duration of postoperative analgesia. To compare the total amount of rescue analgesics used during the 12 hour post operative period. To study the side effects and complications during the post operative period. Timepoint: 12 hours

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Countries

India

Contacts

Public ContactShubham Rahane

Acharya Vinobha Bhave Rural Hospital, JNMC

neetachaudhary123@gmail.com9423421689

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026