To find out the dose of intranasal Dexmedetomidine to provide sedation in children undergoing MRI .

Determination of effective dose of intranasal Dexmedetomidine for successful sedation in paediatric population undergoing magnetic resonanace imaging - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/01/061153

Enrollment

100

Registered

2024-01-05

Start date

Unknown

Completion date

Unknown

Last updated

2024-01-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Dexmedetomidine: Intranasal Dexmedetomidine starting at a dose of 2mcg per kg will be given to the patient 30 minutes before scheduled MRI time.Dixons up and down method will be used ,

Eligibility

Inclusion criteria

Inclusion criteria: -Children of either gender aged 1 to 5 years of age -ASA status I, II -undergoing Non Contrast MRI BRAIN

Exclusion criteria

Exclusion criteria: -Refusal of parentsguardian to give consent -Recent upper respiratory tract infection(URTI)(less than 2 weeks) -Non fasted -Nasal deformity -Anticapated difficult airway

Design outcomes

Secondary

Measure	Time frame
-To investigate the efficacy of single shot intranasal dexmedetomidine for IV cannulation -To determine safety profile of intranasal dexmedetomidine for paediatric MRI. Timepoint: every five minutes after sedation till FASTTRACK >12	—

Primary

Measure	Time frame
To determine the 50% and 95% effective dose of intranasal dexmedetomidine for effective sedation in Indian population undergoing MRI.Timepoint: every five minutes after sedation till FASTTRACK >12	—

Countries

India

Contacts

Public ContactDr Sanjeev Palta

Government Medical College and Hospital, Sector 32, Chandigarh

richajayant@rediffmail.com9646121513

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026