Comparison between opioid free anaestheisa with opioid based general anaesthesia for laparoscopic cholecystectomy.

A Comparative study of effects of opioid free anesthesia with opioid based general anaestheisa in adult patients for elective laparoscopic cholecystectomy- A prospective, randomized, triple blinded study. - Not applicable

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/01/061145

Enrollment

Registered

2024-01-05

Start date

Unknown

Completion date

Unknown

Last updated

2024-01-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Infusion dexmedetomidine loading dose followed by maintainence and infusion lignocaine loading followed by maintainence.: Infusion dexmedetomidine 1mcg/kg/hr followed by maintainence 0.

Eligibility

Inclusion criteria

Inclusion criteria: -ASA-PS grades I - II -Posted for elective laparoscopic cholecystectomy - BMI < 30 Kg/m2

Exclusion criteria

Exclusion criteria: -Patient refusal -Emergency surgery -Pregnancy and breast feeding -Hepatic, renal and cardiac insufficiency -BMI >30 -Allergy and contraindications to drugs

Design outcomes

Primary

Measure	Time frame
Post op analgesic efficacy- post op pain for 24 hours ( VAS every 30 mins for first 2 hours in PACU then @ 4,6,8,12,24 hours) and post op rescue analgesic consumption. Timepoint: 24 hours	—

Secondary

Measure	Time frame
Intra operative hemodynamics - HR,NIBP,MAP Post operative nausea & vomitting. Post operative sedation using modified Ramsay sedation score.Timepoint: 6 hours	—

Countries

India

Contacts

Public ContactVishnu Priya Raj Kumar

Sri Ramachandra Institute of Higher Education and Research

vjram2001@yahoo.co.in9841219820

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026