Yoga and Head & Neck Cancer

Effect of Yogic breathing and Yoga nidra as an adjuvant to standard care for patients with Head and Neck Squamous Cell Carcinomas- A Randomized Control Trial - Nil

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/01/061128

Enrollment

152

Registered

2024-01-04

Start date

Unknown

Completion date

Unknown

Last updated

2024-01-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: C760- Malignant neoplasm of head, face and neck

Interventions

Intervention1: Yoga therapy: Yogic Breathing - 15 minutes Yoga Nidra - 20 minutes Control Intervention1: Standard of Care: Radiotherapy or and Chemotherapy or and Surgical intervention Standard of

Eligibility

Inclusion criteria

Inclusion criteria: 1. Histologically or cytologically confirmed cases 2. Stage - T1 to T4b, NX to N3b and M0 - as per AJCC Staging 3. Functional ability as per Eastern Cooperative Oncology Group Score 0–1 4. Willing to undertake home-based yoga practice

Exclusion criteria

Exclusion criteria: 1. Metastatic HNSCC, 2. Other comorbid conditions, including psychiatry 3. Patients with intravenous antibiotics 4. Exposure to Yoga in the past three months 5. Patients with continued substance abuse

Design outcomes

Primary

Measure	Time frame
EORTC-QLQ-C30 EORTC-QOQ H&N35Timepoint: Day0 Week6 or 7 Week10 0r 11 Week24	—

Secondary

Measure	Time frame
1. Superoxide dismutase (SOD) 2. Malondialdehyde (MDA) 3. Systemic immune inflammation index (SIII) 4. Systemic Inflammation Response Index (SIRI) 5. Modified Glasgow prognostic score (mGPS) 6. Montreal Cognitive Assessment (MoCA) 7. The Distress thermometer (DT) 8. Depression, Anxiety, & Stress Scale questionnaire (DASS- 21) 9. Pittsburgh Sleep Quality Index 10. EORTC FA-12 (Cancer-Related Fatigue Module) Timepoint: Day0 Week6 or 7 Week10 0r 11 Week24	—

Measure

Time frame

1. Superoxide dismutase (SOD) 2. Malondialdehyde (MDA) 3. Systemic immune inflammation index (SIII) 4. Systemic Inflammation Response Index (SIRI) 5. Modified Glasgow prognostic score (mGPS) 6. Montreal Cognitive Assessment (MoCA) 7. The Distress thermometer (DT) 8. Depression, Anxiety, & Stress Scale questionnaire (DASS- 21) 9. Pittsburgh Sleep Quality Index 10. EORTC FA-12 (Cancer-Related Fatigue Module) Timepoint: Day0 Week6 or 7 Week10 0r 11 Week24

—

Countries

India

Contacts

Public ContactNJ Patil

Centre for Integrative Medicine and Research, MAHE Manipal [CIMR]

ayushnitin@gmail.com919886211008

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026