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Comparison of effect of ketamine and Paracetamol with Paracetamol alone on reduction of pain, nausea and vomiting after adenotonsil surgery in children

A Comparative study of effect of administration of Ketamine and Paracetamol versus Paracetamol on postoperative pain, nausea and vomiting after pediatric Adenotonsillectomy - NIL

Status
Active, not recruiting
Phases
Phase 3Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/01/061116
Enrollment
80
Registered
2024-01-04
Start date
Unknown
Completion date
Unknown
Last updated
2024-01-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Inj ketamine (0.25mg/kg) and Inj paracetamol(15mg/kg): With due approval from institutional ethical committee, a prospective randomized double-blind study has been planned on 80 pediatr

Sponsors

JLN Medical College
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients posted for elective adenotonsillectomy ASA physical status 1 and 2

Exclusion criteria

Exclusion criteria: Age 12 years Emergency surgery Patient refusal Patient sensitive/ allergic to any of the drugs Patient with neuropsychiatric illness cardiovascular disease patient Coagulopathies Hepatic and Renal disease

Design outcomes

Primary

MeasureTime frame
Duration of analgesia and assesesment of pain.Timepoint: Assessment of Children Hospital of Eastern Ontario Pain Scale (CHEOPS) in young children in postoperative period at immediatly after extubation,15 min, 30 min, 1hr,2hr,4hr,6hr and 12 hours.

Secondary

MeasureTime frame
Duration of postoperative analgesia Postoperative nausea & vomiting (PONV)Timepoint: Assessment of time of demand of rescue analgesia. Assessment of episodes of nausea & vomiting after extubation, 15 min, 30 min,1 hr,2 hr,4 hr,6 hr & 12 hour.

Countries

India

Contacts

Public ContactDr Veena Mathur

JLN Medical College, Ajmer

veenamathur41@gmail.com9460517947

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026