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A study done to evaluate the usefulness of changes in a non- invasive parameter called End Tidal Carbon Dioxide after giving fluid infusion to neurosurgery patients to predict whether they will respond with an increase in cardiac output

A prospective observational study to evaluate the utility of changes in end tidal carbon dioxide to assess fluid responsiveness after volume expansion in patients undergoing neurosurgery in supine position - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2024/01/061105
Enrollment
40
Registered
2024-01-04
Start date
Unknown
Completion date
Unknown
Last updated
2024-01-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: G968- Other specified disorders of central nervous system

Interventions

Intervention1: Nil: Nil Control Intervention1: Nil: Nil

Sponsors

Dr. Anjali R Hegde
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.ASA I & II patients 2.Patients aged above 18years 3.Patients undergoing neurosurgery in supine position under general anaesthesia

Exclusion criteria

Exclusion criteria: 1. Patients with cardiac arrhythmias, valvular heart diseases or left or right heart failure 2. Patients with chronic obstructive pulmonary disease with a MMRC Dyspnea Scale 3 or more 3. Patients with intrathoracic lesions 4. Pregnant women 5. Patients on vasoactive drugs

Design outcomes

Primary

MeasureTime frame
Change in End tidal carbon dioxide after volume expansion to predict fluid responsiveness defined as fall in Pleth Variability Index to less than 14 percent and increase in SBP by 10 mm Hg or moreTimepoint: Baseline, 1 min, 3 min, 5 mins and 10 mins after completion of infusion.—

Secondary

MeasureTime frame
Pleth Variability Index and Pulse Pressure VariationTimepoint: Baseline, 1 min, 3 min, 5 mins and 10 mins after completion of infusion.—

Countries

India

Contacts

Public ContactDr Surekha C

Bangalore Medical College and Research Institute

suri.c13@gmail.com9845489724

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026