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TO ESTIMATE AND CORRELATE LEVELS OF GHRELIN AND LEPTIN IN GINGIVAL CREVICULAR FLUID OF HEALTH, CHRONIC GENERALIZED PERIODONTITIS OF PATIENTS WITH AND WITHOUT OBESITY – A CLINICO-BIOCHEMICAL STUDY ?.

“ESTIMATION AND CORRELATION OF GHRELIN AND LEPTIN IN GINGIVAL CREVICULAR FLUID OF HEALTH, CHRONIC GENERALIZED PERIODONTITIS OF SUBJECTS WITH AND WITHOUT OBESITY – A CLINICO-BIOCHEMICAL STUDY ?.

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2024/01/061099
Enrollment
36
Registered
2024-01-03
Start date
Unknown
Completion date
Unknown
Last updated
2024-01-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: Z68- Body mass index [BMI]

Interventions

None listed

Sponsors

DR. G.NAGATULSI
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: · Subjects of either sex, between the ages of 20 years and 60 years. · Presence of at least 20 natural teeth. · Individuals with healthy periodontium. Subjects with normal lipid profile having BMI values as given by Asian Specific Perspective Obesity-WHO 2000. 1.BMI in range of 18.5-22.9 kg/m2 in non-obese Waist circumference (WC) men : WC= 90cm women : WC=80cm 2. BMI in range of 25-29.9 kg/m2 in obese men : WC =90cm women : WC =80cm · Patients with diagnosis of generalized stage III grade B periodontitis. (Periodontal health, gingivitis and periodontitis definition will be based on the classification of periodontal and peri-implant diseases and conditions as proposed in 2017 World Workshop).

Exclusion criteria

Exclusion criteria: · Individuals who have received periodontal therapy in the last 6 months. · Individuals with systemic diseases other than type 2 diabetes mellitus (HbA1c · Smokers.

Design outcomes

Primary

MeasureTime frame
· To estimate the levels of Ghrelin and leptin in GCF of subjects in health and chronic periodontitis with or without obesity at baseline. · To correlate the levels of Ghrelin and leptin in GCF of subjects in health and chronic periodontitis with or without obesity at baseline. · To explore the possibility of using Ghrelin and leptin as a marker for inflammation in generalized stage III grade B periodontitis and relate them with clinical parameters at baseline. Timepoint: · To estimate the levels of Ghrelin and leptin in GCF of subjects in health and chronic periodontitis with or without obesity AT THE BASELINE · To correlate the levels of Ghrelin and leptin in GCF of subjects in health and chronic periodontitis with or without obesity AT BASE LINE · To explore the possibility of using Ghrelin and leptin as a marker for inflammation in generalized stage III grade B periodontitis and relate them with clinical parameters AT BASE LINE.—

Secondary

MeasureTime frame
Ghrelin and leptinTimepoint: Before treatment—

Countries

India

Contacts

Public ContactDRGNAGATULSI

THE OXFORD DENTAL COLLEGE

sunaina1096@gmail.com9742420669

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026