Comparative Analysis of Esmolol and Dexmedetomidine for Optimal Surgical Field Conditions in Functional Endoscopic Sinus Surgeries: A Prospective Randomized Clinical Study

A prospective randomised clinical study to compare the Effects of Esmolol and Dexmedetomidine and their effectiveness to provide quality surgical field during Functional Endoscopic Sinus Surgeries - NIL

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/01/061084

Enrollment

Registered

2024-01-03

Start date

Unknown

Completion date

Unknown

Last updated

2024-01-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: J324- Chronic pansinusitis

Interventions

Intervention1: comparison of two drugs (Esmolol and Dexmedetomidine): Effects of Esmolol and Dexmedetomidine and their effectiveness to provide quality surgical field during Functional Endoscopic Sinu

Eligibility

Inclusion criteria

Inclusion criteria: body weight 40kg to 70kg, ASA grade I or II, scheduled for surgery under General Anaesthesia

Exclusion criteria

Exclusion criteria: patient not willing to participate in the study uncooperative patient, patients with a history of drug allergies, patients with pre-existing disease like asthma, hepatic or renal dysfunction, pregnant or lactating, morbidly obese patient

Design outcomes

Primary

Measure	Time frame
Haemodynamic parameters like heart rate, systolic blood pressure, diastolic blood pressure and mean arterial blood pressure from baseline at different time intervals in both groups that is, group receiving esmolol and the group receiving dexmedetomidine during Functional Endoscopic Sinus Surgeries.Timepoint: 1 year and 6 months	—

Secondary

Measure	Time frame
Emergence time, sedation score, VRS scale score in post-operative field and time to first rescue analgesic after surgeryTimepoint: 1 year and 6 months;Proportion of cases with complications.Timepoint: 1 year and 6 months;Quality of intra-operative surgical field by using average categorical scale in both groups.Timepoint: 1 year and 6 months	—

Countries

India

Contacts

Public ContactRatan L

Jawar Lal Nehru Medical college and Hospital

mainasingh111@gmail.com9414097045

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026