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A randomised trial to compare lignocaine spray with intracervical lignocaine injection for pain relief during office endometrial biopsy

A randomised study to compare lignocaine spray over the cervix with intracervical lignocaine injection for analgesia during office endometrial biopsy - nil

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/01/061038
Enrollment
106
Registered
2024-01-02
Start date
Unknown
Completion date
Unknown
Last updated
2024-01-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: N939- Abnormal uterine and vaginal bleeding, unspecified

Interventions

Intervention1: intracervical lignocaine injection: 1 percent lignocaine injection will be given intracervically Intervention2: 10 percent lignocaine spray: 4 puffs of 10 percent lignocaine spray will

Sponsors

pgimer
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: women undergoing office endometrial biopsy for various indications

Exclusion criteria

Exclusion criteria: pregnant women ,uterus size more than 12 week, known hypersensitivity to lignocaine and NSAIDs ,pid, any previous surgery on cervix,medical disorders like bronchial asthma, cardiovascular disorders , uncontrolled hypertension or diabetes ,moderate or severe anaemia

Design outcomes

Primary

MeasureTime frame
severity of pain perceived by the women during office endometrial biopsyTimepoint: severity of pain perceived by the women during office endometrial biopsy and 15-30 minutes post procedure

Secondary

MeasureTime frame
adequacy of sampleTimepoint: histopathology report will be collected 2 weeks post procedure;complications during the procedureTimepoint: measuring bp and PR before and after the procedure;ease of insertion of Karman cannulaTimepoint: will be rated as easy and difficult

Countries

India

Contacts

Public ContactDr Surbhi Sharma

Post graduate institute of medical education and research

rashmibagga@gmail.com9872494602

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026