Development of Sidhartaka Snanayoga ointment and comparing its effect with its lepa in hyperpigmentation in contact derrmatitis

Development of a value-added formulation of sidhartaka snanayoga and its pilot clinical study as an add on to aragwadhadi gana kashaya in hyperpigmentation associated with subacute contact dermatitis - NIL

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/01/061024

Enrollment

Registered

2024-01-01

Start date

Unknown

Completion date

Unknown

Last updated

2024-06-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: L249- Irritant contact dermatitis, unspecified cause

Interventions

None listed

Eligibility

Inclusion criteria

Inclusion criteria: Participants diagnosed with hyperpigmentation associated with localised, subacute contact dermatitis Subacute contact dermatitis: crusts, scales, and hyperpigmentation

Exclusion criteria

Exclusion criteria: Severe conditions of Contact dermatitis with an extensive skin area involvement (greater than 20 percent) Pregnant women and lactating mothers Under medications of antibiotics, steroids and topical steroids Patients diagnosed with severe systemic disorders Already diagnosed with or a history of other skin conditions such as psoriasis Drug induced bullous disorders Tinea corporis Contact urticaria syndrome Asteatotic eczema

Design outcomes

Primary

Measure	Time frame
HyperpigmentationTimepoint: Assessment will be done on the 0th day, 16th day and 31st day	—

Secondary

Measure	Time frame
Histopathological changes such as Scale crust in stratum corneum Orthokeratosis or Parakeratosis Acanthosis Acantholysis Spongiosis Pyknosis Intra epithelial neutrophils & eosinophils Epidermal necrosis Micro abscess Melano phages Edema of papillary dermis Perivascular infiltrate of lymphocytes Timepoint: 0th day & 31st day from a subset of 6 participants from each group	—

Countries

India

Contacts

Public ContactDr Rajmohan V

Government Ayurveda medical College and Hospital

sow.poothyottuvaidyasala@gmail.com8921057954

Outcome results