Mannitol added with local anaesthesia for removal of lower 3rd molar tooth .

EFFICACY OF 0.5M MANNITOL AS AN ADJUVANT WITH LIGNOCAINE WITH ADRENALINE FOR CLASSICAL INFERIOR ALVEOLAR NERVE BLOCK IN MANDIBULAR IMPACTED THIRD MOLAR EXTRACTIONS. RANDOMIZED CLINICAL TRIAL - nil

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/01/061022

Enrollment

Registered

2024-01-01

Start date

Unknown

Completion date

Unknown

Last updated

2024-01-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K011- Impacted teeth

Interventions

Intervention1: mannitol 20%: 1.5 ml of 2% lignocaine with 1:80,000 adrenaline and 0.9 ml of 0.5M mannitol Control Intervention1: habimunirunisa: nil Control Intervention2: Local anaesthesia: 2% lign

Eligibility

Inclusion criteria

Inclusion criteria: 1.Patients classified under ASA I and II. 2.Patients requiring surgical extraction of impacted bilateral mandibular third molars. 3.Patients who can comprehend the pain scale used in the study

Exclusion criteria

Exclusion criteria: 1. Patients classified under ASA III or greater 2. Patients under influence of alcohol. 3. Pregnant or lactating women 4. Patients with known allergies to any of the components of local anesthesia or mannitol. 5. Patients with psychiatric illness

Design outcomes

Primary

Measure	Time frame
1) Onset of Anesthesia 2) Duration of Anesthesia Timepoint: 0 hr to 3hrs	—

Secondary

Measure	Time frame
1) Duration of AnalgesiaTimepoint: 0 hrs to 24 hrs	—

Countries

India

Contacts

Public ContactDr Habimunirunisa

rajarajeswari dental college

rohit.srikanthan@gmail.com9845439046

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026