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A research study to compare pain relief between external oblique intercostal plane block and intravenous morphine in upper abdominal surgeries

A prospective randomised trial comparing postoperative pain relief between bilateral external oblique intercostal plane block and intravenous morphine in patients after upper abdominal surgeries - NIL

Status
Active, not recruiting
Phases
Phase 3Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/01/060995
Enrollment
66
Registered
2024-01-01
Start date
Unknown
Completion date
Unknown
Last updated
2025-02-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: C168- Malignant neoplasm of overlappingsites of stomach

Interventions

Intervention1: External Oblique Intercostal Block: Bilateral ultrasound guided EOIB will be given in the postoperative period if the patient complains of pain with an NRS greater than 3 using a linear

Sponsors

Nivedhyaa
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: All patients who report moderate to severe upper abdominal pain, defined as a pain score on the numerical rating scale (NRS) of 0-10 as 4 or above for the first three days (POD 0,1,2 and 3) at rest or due to movement or spirometry, in the postoperative period will be included both elective and emergency surgeries 2.Patient who have given informed consent for the procedure. 3.Age of 18 and above 4, Surgeries with upper abdominal incisions including gastric surgeries, splenectomy, cholecystectomy, hepatectomy will be included for the study.

Exclusion criteria

Exclusion criteria: 1.renal diseases with elevated serum creatinine level more than 1.5mg% 2.Local skin site infection at the site of epidural or at the site of the EOIPB as identified before surgery 3.Patient refusal to give consent for epidural or blocks 4.History of known allergies to local anaesthetics or morphine .Suspected bowel obstruction : in this case we cannot use opioids 6.Patient would get discharged in less than 24 hours. 7.Drowsy patient who cannot tell about the pain score appropriately 8.Patients in whom epidural catheter will not be placed (as known preoperatively due to low platelet count or altered coagulation profile) 9.Patients who have been treated with tablet morphine in the preoperative period for pain

Design outcomes

Primary

MeasureTime frame
Mean requirement of intravenous morphine in either groups as rescue analgesicTimepoint: Mean requirement of intravenous morphine in either groups as rescue analgesic upto 24 hours

Secondary

MeasureTime frame
Pain Intensity Difference Side Effects Sum of the pain intensity differenceTimepoint: 24 hours

Countries

India

Contacts

Public ContactNivedhyaa S

Cancer Institute (WIA),Adyar

nivedhyaa@gmail.com9597423654

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026