A Clinical trail comparing different materials in treatment of completly formed teeth.

A comparative evaluation of PRF and amniotic membrane scaffolds in regenerative endodontic therapy of permanent mature teeth with necrotic pulp. - nil

Status

Active, not recruiting

Phases

Phase 2Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2023/12/060979

Enrollment

Registered

2023-12-29

Start date

Unknown

Completion date

Unknown

Last updated

2024-01-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K041- Necrosis of pulp

Interventions

Intervention1: regenerative endodontic treatment using amniotic membrane scaffold.: Under local anesthesia, access cavity will be preapared, and the tooth will be isolated with a rubber dam. Negotiati

Eligibility

Inclusion criteria

Inclusion criteria: 1.Necrotic mature, permanent anterior teeth. 2. Closed apex associated with or without periapical radiolucency less than 1.5 cm 3. Negative response to thermal test and electric pulp testing 4. Tooth with large pulp chamber 5. No tooth mobility and <3 mm pocket depth

Exclusion criteria

Exclusion criteria: 1. Patients with medical conditions like cardiac problems, pregnant patients, diabetic patients, bleeding tendencies, HIV+ patients, hepatitis-B. All patients will go through HIV screening 2. Tooth that requires post and core, severely curved canals. 3. Tooth with calcified canals.

Design outcomes

Primary

Measure	Time frame
HEALING OF PERIAPICAL LESION.Timepoint: 6 MONTHS,12 MONTHS	—

Secondary

Measure	Time frame
REGAINING OF SENSIBILITY TO THERMAL AND ELECTRIC PULP TESTS.Timepoint: 6 MONTHS,12 MONTHS	—

Countries

India

Contacts

Public ContactBurugupalli Swetha

Faculty of Dental Sciences,IMS,BHU

dr.neelammittal@gmail.com9133527164

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026