Skip to content

Effect of a brain stimulation technique on activity of brain regions in people with mild cognitive impairment. The purpose of this study is to test a new brain stimulation technique for improving memory problems in people with mild cognitive impairment.

Effect of transcranial theta-gamma stimulation technique on default mode network activity and connectivity in individuals with mild cognitive impairment: A pilot randomized placebo-controlled trial. - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2023/12/060976
Enrollment
20
Registered
2023-12-29
Start date
Unknown
Completion date
Unknown
Last updated
2024-01-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: G30-G32- Other degenerative diseases of the nervous system

Interventions

Intervention1: Transcranial electrical stimulation.: The transcranial theta-gamma noise stimulation targeting posterior cingulate cortex and parahippocampus will be delivered for a single session of 3

Sponsors

Shivani Mhaskar
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. English or Kannada speaking 2. Subjective memory complaints 3. 0.5 score on Clinical Dementia Rating 4. 18-25 score on Montreal Cognitive assessment 5. Preserved daily functions 6. Without symptoms of Dementia 7. Presence of a care-taker for reporting of memory problems of the participant.

Exclusion criteria

Exclusion criteria: 1. Cognitive decline due to causes or conditions other than amnestic mild cognitive impairment 2.Enrolment in other tentative drug or trial study during the period of trial 3.History of seizures or epilepsy or other neurological disorders 4. Migraine or vertigo 5.Dizziness or balance disorders 6. Any other psychiatric conditions like schizophrenia or bipolar disorders or personality disorders or major depressive disorders 7. Substance abuse disorders 8.Cardiac pacemakers or metal implants in head and neck regions

Design outcomes

Primary

MeasureTime frame
1.Feasibility measures: -Recruitment rate -Drop-out rates -Acceptibility of the intervention - Safety of the intervention using Adverse Effects Questionnaire 2.Resting state EEG Timepoint: 1. Before intervention 2.Immediately after intervention

Secondary

MeasureTime frame
1. Montreal Cognitive Assessment 2.Trail Making Test A and B 3. Pattern Recognition MemoryTimepoint: 1. Before intervention 2. Immediately after intervention

Countries

India

Contacts

Public ContactShivani Mhaskar

Manipal College of Health Professions

adhia.divya@gmail.com

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026