Skip to content

Effect on Craving in Individuals with Alcohol Use Disorder

Effect of Cathodal High Definition Transcranial Direct Current Stimulation (HD-tDCS) over Left Dorso-Medial Prefrontal Cortex on Craving and Alcohol Consumption in Individuals with Alcohol Use Disorder – A Pilot, Double-blind, Sham-controlled Randomized Clinical Trial - DRIVE Pilot Study

Status
Active, not recruiting
Phases
Phase 2Phase 3
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2023/12/060972
Enrollment
40
Registered
2023-12-29
Start date
Unknown
Completion date
Unknown
Last updated
2024-01-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: F102- Alcohol dependence

Interventions

Intervention1: HD-tDCS. High Definition Transcranial Direct Current Stimulation: Group 1- The participants of the first group will be administered active cathodal HD- tDCS session for 20 minutes incl

Sponsors

Postgraduate Institute of Medical Education and Research Chandigarh
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Providing written informed consent 2. A diagnosis of Alcohol Use Disorder as per DSM 5 TR. 3. A minimum 4 weeks of maintenance treatment on Naltrexone or Acamprosate or Baclofen or Topiramate 4. Subjective report of Craving severity greater than 2 on the 5-point Visual Analogue Scale

Exclusion criteria

Exclusion criteria: 1. Patients with comorbid substance use disorders other than Alcohol and Nicotine. 2. Patients with primary psychotic or primary mood disorders. 3. Patients with a neurological disorder like multiple sclerosis, stroke, epilepsy, or encephalopathy due to any cause. 4. Patients with any intracranial metallic and electric implants. 5. Patients with comorbid organic brain syndrome and intellectual disability. 6. Pregnant and lactating females. 7. Any electronic or metallic implant.

Design outcomes

Primary

MeasureTime frame
Acceptability and Feasibility of the HD-tDCS in patients of alcohol use disorder.Timepoint: 4 weeks

Secondary

MeasureTime frame
Effectiveness & tolerability of HD-tDCS in patients of alcohol use disorderTimepoint: 4 weeks

Countries

India

Contacts

Public ContactChahat Jamwal

Postgraduate Institute of Medical Education and Research

drshalini.anji@gmail.com9886313489

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026