Comparative clinical efficacy of Varun Twak Lepa and Krushnatiladi Lepa in Vyanga(Melasma)

Pharmaceutico Analytical study of modified dosage forms (Lepa guti) of Varun Twak Lepa and Krushnatiladi Lepa and their comparative clinical evaluation in Vyanga (Melasma) – A Randomized Controlled Trial - NIL

Status

Active, not recruiting

Phases

Phase 3Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2023/12/060971

Enrollment

Registered

2023-12-29

Start date

Unknown

Completion date

Unknown

Last updated

2024-01-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: L811- Chloasma

Interventions

None listed

Eligibility

Inclusion criteria

Inclusion criteria: • Patients willing for participation in the study & ready to give written informed consent. • Patients between the age group of 18-50 years will be selected for study. • Patients irrespective of sex, caste, religion, occupation, economic status and will be selected for the study. • Chronicity less than 5 years will be selected. • Patients with clinical features of Vyanga as per Ayurvedic classics will be included.[2] • Pregnancy & Lactating woman having Vyanga. • Von Luschan’s Color Scale ranging from 17 to 30.

Exclusion criteria

Exclusion criteria: • Patients with past and present history of any skin diseases e.g. Psoriasis, Dermatitis, Vitiligo etc. • Person suffering from any bacterial or fungal infection, viral infection with antibiotics, antifungal and antiviral drugs. • Patients with rashes over face and open wound at face. • Patients with history of hyperpigmentation since birth like Neavus of Ota, tumours like malignant melanoma, drug induced Pigmentation changes etc • Patient suffering with systemic disorders like renal failure, hepatic disorder. • Patients with known case of endocrinal disorders like Addison’s disease, Cushing’s disease. Acne, etc. • Person with big or dark scars on face.

Design outcomes

Primary

Measure	Time frame
To evaluate efficacy of Krushnatiladi Lepa Guti in Vyanga(Melasma) with Melasma Severity index ScoreTimepoint: 30 days	—

Secondary

Measure	Time frame
To evaluate efficacy of Varun Twak Lepa Guti in Vyanga(Melasma) with Melasma Severity index ScoreTimepoint: 1 Month	—

Countries

India

Contacts

Public ContactPratiksha Mahure

Datta Meghe Institute of Higher Education & Research

bharatrathi174@gmail.com9011058301

Outcome results