A clinical trial to assess postoperative analgesic effects of ultrasound guided Quadratus lumborum block with dexmedetomidine in children undergoing laparoscopic surgeries

Efficacy of ultrasound guided Quadratus lumborum block with dexmedetomidine in providing postoperative analgesia after laparoscopic surgeries in children - A randomised control trial - nil

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2023/12/060885

Enrollment

Registered

2023-12-28

Start date

Unknown

Completion date

Unknown

Last updated

2024-05-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K353- Acute appendicitis with localizedperitonitis Health Condition 2: K402- Bilateral inguinal hernia, withoutobstruction or gangrene Health Condition 3: Q632- Ectopic kidney Health Condition 4: O- Medical and Surgical Health Condition 5: N832- Other and unspecified ovarian cysts Health Condition 6: N432- Other hydrocele Health Condition 7: K458- Other specified abdominal hernia without obstruction or gangrene Health Condition 8: K429- Umbilical hernia without obstruction or

Interventions

Intervention1: Ultrasound guided Quadratus lumborum block with bupivacaine and dexmedetomidine: 0.8ml/kg of 0.25% Bupivacaine with 1 microgram/kg of dexmedetomidine with appropriate amount of saline g

Eligibility

Inclusion criteria

Inclusion criteria: All children ASA1/2 posted for elective laparoscopic surgeries will be included in the study

Exclusion criteria

Exclusion criteria: 1. ASA 3/4 2. History of liver and renal disorders 3. Coagulopathies and bleeding disorder 4. Infection at injection site 5. Allergy to local anaesthetic/ paracetamol 6. Patient and Guardian refusal

Design outcomes

Primary

Measure	Time frame
Time to first analgesicTimepoint: 1. Time from block given till patient has a pain score of more than 3 is observed. 2. Pain scores will be assessed from 0,5,10,30 minutes, 1,1.5,2,6,12,18,24,36 hours post extubation. 3. patient has a pain score of more than 3 within 6 hours of paracetamol, he/ she will be given Ibuprofen 7 mg/kg body weight.	—

Secondary

Measure	Time frame
Intraoperative & Postoperative complicationsTimepoint: during intraoperative & in postoperative period Incidence of bradycardia, hypotension, respiratory depression, vomiting & pruritis will be noted;Post operative pain scoresTimepoint: Every 5 minutes post extubation, at 30 minutes, 1 hour, 1 1/2 hours, 2 hours, 6 hours, 12 hours,18 hours, 24 hours, 36 hours post extubation;Requirement of rescue analgesicTimepoint: Requirement of rescue analgesic Ibuprofen 7mg/kg in addition to paracetamol if pain score more than 3 during 36 hours post block ;Total paracetamol dosesTimepoint: Total number of paracetamol doses given in the first 36 hours post block	—

Measure

Time frame

Intraoperative & Postoperative complicationsTimepoint: during intraoperative & in postoperative period Incidence of bradycardia, hypotension, respiratory depression, vomiting & pruritis will be noted;Post operative pain scoresTimepoint: Every 5 minutes post extubation, at 30 minutes, 1 hour, 1 1/2 hours, 2 hours, 6 hours, 12 hours,18 hours, 24 hours, 36 hours post extubation;Requirement of rescue analgesicTimepoint: Requirement of rescue analgesic Ibuprofen 7mg/kg in addition to paracetamol if pain score more than 3 during 36 hours post block ;Total paracetamol dosesTimepoint: Total number of paracetamol doses given in the first 36 hours post block

—

Countries

India

Contacts

Public ContactDr Aruna Parameswari

Sri Ramachandra Medical College and Research Institute

hod.anaesthesiology@sriramachandra.edu.in09840529863

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026