Health Condition 1: J99- Respiratory disorders in diseasesclassified elsewhere
Conditions
Interventions
Intervention1: NIL: NIL
Control Intervention1: NIL: NIL
Sponsors
Dr Amrita Bhattacharya
Eligibility
Inclusion criteria
Inclusion criteria: i.Patients admitted with acidotic, hypercarbic COPD exacerbation. ii. Age > 18 yrs and = 8yrs.
Exclusion criteria
Exclusion criteria: 1.Pre-existing diaphragmatic dysfunction or neuromuscular diseases affecting diaphragmatic function 2. Pregnant women 3. Contraindications to the sniff test or absence of a window on ultrasound examination 4. Inability to sit up for the fluoroscopy or USG examination 5. Patients who are frail, bedbound, end stage organ damage, malignancy 6.NIVO score being either too low (0–2) or too high (7 to 9).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The correlation between diaphragm dysfunction as assessed by ultrasonographically measured excursion and fluoroscopy-measured excursion during a sniff maneuver at three key time points: •Upon admission •At ICU discharge •At a 3-month follow-up Timepoint: •Upon admission •At ICU discharge •At a 3-month follow-up | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. The difference in total duration of NIV usage between patients with and without diaphragm dysfunction 2.the incidence of NIV failure 3. Mortality rates 4. MRCD dyspnea scores 5. levels of functional impairmentTimepoint: At 3 months post discharge | — |
Countries
India
Contacts
Public ContactDr Amrita Bhattacharya
The Calcutta Medical Research Institute
Outcome results
None listed