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removal of whole blood before surgery and transfusing the blood after major blood loss helps to reduce the need of transfusing blood taken from bloodbank in patients undergoing major head and neck surgeries.

Effect of acute normovolemic hemodilution on requirement of allogenic blood transfusion in patients undergoing major head and neck surgeries. - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2023/12/060791
Enrollment
48
Registered
2023-12-26
Start date
Unknown
Completion date
Unknown
Last updated
2024-01-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: C069- Malignant neoplasm of mouth, unspecified

Interventions

Intervention1: acute normovolemic hemodilution: After induction of general anesthesia and insertion of the arterial line, blood will be collected from antecubital vein of the upper arm which is in opp

Sponsors

Amrita Institute of Medical Sciences
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Age – 18-60 years ASA – I and II

Exclusion criteria

Exclusion criteria: Preoperative Anemia(Hb- Severe liver disease (Child Pugh score B or C ) Severe Heart failure(NYHA 3or 4) ESRD requiring intermittent haemodialysis Coagulation disorders Infectious disorders

Design outcomes

Primary

MeasureTime frame
Comparison of need for allogenic blood transfusion after acute normovolemic hemodilution (ANH) in patients undergoing head and neck surgeries with anticipated major blood loss with patients receiving standard care.Timepoint: end of tumour resection. need for allogenic blood transfusion will be assessed till 48 hours postoperatively—

Secondary

MeasureTime frame
To assess the effect of acute normovolemic hemodilution on hemodynamic parameters, need for inotropes, adverse events of blood transfusion and length of hospital stay as compared with group who receive standard care without ANH.Timepoint: preoperative ,after donation and at the end of surgery—

Countries

India

Contacts

Public ContactRONIYA ANN ROY

Amrita institute of medical sciences cochin

sunilrajan@aims.amrita.edu09074984098

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026