To compare vortioxetine and escitalopram in the management of major depressive disorder.

A comparative study of vortioxetine and escitalopram on efficacy, tolerability and effects on metabolic parameters in the management of major depressive disorder in a tertiary care hospital. - Nil

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2023/12/060774

Enrollment

Registered

2023-12-26

Start date

Unknown

Completion date

Unknown

Last updated

2024-01-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: Subjects diagnosed as major depressive disorder treated with tablet vortioxetine: tablet vortioxetine 10 mg once at night and will be followed up on baseline, week 4th and week 12th Con

Eligibility

Inclusion criteria

Inclusion criteria: 18-45 years of male and female, diagnosed as case of major depressive disorder, not been treated for the index episode.

Exclusion criteria

Exclusion criteria: Subjects with comorbid psychiatric disorder except for the comorbid anxiety symptoms and tobacco use, known case of diabetes or hypertension or dyslipidemia or hyperthyroidism, hypothyroidism, with medical or surgical condition that affect his or her locomotor capabilities, pregnancy and lactating female.

Design outcomes

Primary

Measure	Time frame
To assess the efficacy, tolerability and metabolic parameters on subjects treated with vortioxetine versus escitalopram in the management of major depressive disorder.Timepoint: At baseline, week 4th and week 12th	—

Secondary

Measure	Time frame
To assess the treatment adverse effects responsible for intolerance of vortioxetine and escitalopram by using the anti depressant side effect checklist.Timepoint: Baseline, week 4, week 12.;To study the association of efficacy and tolerability of vortioxetine and escitalopram in the management of major depressive disorder.Timepoint: Baseline, week 4, week 12.	—

Countries

India

Contacts

Public ContactSuravi Das

Eras lucknow medical college and hospital

docaleem@gmail.com7607358897

Outcome results