A study to evaluate the efficacy of bolus plasmalyte(type of intravenous fluid) in reducing fall in blood pressure after pressure bandage release in lower limb surgeries.

Evaluation of efficacy of bolus plasmalyte in reducing hypotension following tourniquet release in patients undergoing lower limb surgery under spinal anaesthesia. - NIL

Status

Active, not recruiting

Phases

Phase 1Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2023/12/060773

Enrollment

Registered

2023-12-26

Start date

Unknown

Completion date

Unknown

Last updated

2024-01-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: I958- Other hypotension Health Condition 2: I958- Other hypotension

Interventions

Control Intervention1: PLASMALYTE: Patients undergoing lower limb surgeries under spinal anaesthesia with tourniquet application will be given 250 ml bolus of plasmalyte intravenously over a period of

Eligibility

Inclusion criteria

Inclusion criteria: American Society of Anaesthesiologists Physical Status Grade I and II undergoing lower limb surgery under spinal anaesthesia

Exclusion criteria

Exclusion criteria: Patients with known cardiovascular disease and on cardiac medications Pregnant patients

Design outcomes

Primary

Measure	Time frame
Duration of infation and deflation of the tourniquetTimepoint: Time from the inflation of tourniquet till its release.	—

Secondary

Measure	Time frame
hemodynamic parameters ,additional fluid/vasopressor requirementTimepoint: Parameters including heart rate ,systolic blood pressure,diastolic blood pressure,mean arterial pressure will be recorded from baseline,before and after spinal anaesthesia ,before and after the deflation of tourniquet for every 5 min till 30 minutes	—

Countries

India

Contacts

Public ContactDr Dharam Singh Meena

Vardhman Mahavir Medical College and Safdarjung Hospital ,New Delhi

dharams_meena@yahoo.com9910277131

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026