Health Condition 1: I502- Systolic (congestive) heart failure
Conditions
Interventions
Intervention1: Yoga-CaRe programme: Yoga based cardiac rehabilitation(Yoga-CaRe)programme participants will receive 20 supervised sessions spread over a period of three months scheduled twice a week f
Sponsors
Indian Council of Medical Research (ICMR)
VGST KSTEPS
Eligibility
Inclusion criteria
Inclusion criteria: Patients suffering from HF and healthy individuals will be selected for the study. The inclusion criteria for study eligibility for HF patients will be as follows: Male and female patients above 18 years; Physician diagnosed HF based on ESC guidelines, and patients should be NYHA class II/III; HF with reduced ejection fraction = 40%.
Exclusion criteria
Exclusion criteria: Comorbid disease or behavioral or other limitations that interfere with performing Yoga training or prevent the completion of 1 y of exercise training; Elective Cardiovascular procedure or hospitalization planned in the coming 3 months; Heart failure secondary to significant correctable/reversible cause like primary valvular disease/ correctable congential heat disease; participation in exercise training/yoga at regular intervals (more than once per week) at a moderate-to-vigorous intensity at any time in the last 6 weeks; and participation in other clinical trials.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Primary outcomes are change in the flow mediated dilatation (FMD: endothelial dependent) or brachial artery reactivity and functional exercise capacity (6-minute walk test).Timepoint: 3 months | — |
Secondary
| Measure | Time frame |
|---|---|
| 1.Secondary outcomes are changes in arterial compliance & stiffness, biomarkers of endothelial dysfunction, oxidative stress & inflammation 2.Rapid changes in global gene expression profiles in the peripheral blood mononuclear cells following the immediate practice of Yoga CaRe for seven days.Timepoint: 3 months | — |
Countries
India
Contacts
Public ContactDr Satish G Patil
SDM College of Medical Sciences and Hospital
Outcome results
None listed