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COMPARISON OF LEVETIRACETAM AND SODIUM VALPROATE MONOTHERAPY IN CHILDHOOD EPILEPSY

COMPARISON OF EFFICACY AND SIDE EFFECTS OF LEVETIRACETAM AND SODIUM VALPROATE MONOTHERAPY IN CHILDHOOD EPILEPSY –AN OPEN LABEL RANDOMIZED CONTROL TRIAL - nil

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2023/12/060737
Enrollment
52
Registered
2023-12-26
Start date
Unknown
Completion date
Unknown
Last updated
2024-01-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: G409- Epilepsy, unspecified

Interventions

Intervention1: LEVETIRACETAM: Among the newer AEDs levetiracetam which is commonly used, high efficacy and tolerability as monotherapy in children can reduce seizure episodes by more than 50% in major
behavioral side effects as anger, irritability & tantrums , gastrointestinal side effect in form of nausea & gastritis ,weight gain and hair loss is seen.so to see if there is any better antiepilept

Sponsors

DR TARANG KALARIA
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Children 1 year to 18 years of age with newly diagnosed epilepsy.

Exclusion criteria

Exclusion criteria: (1) Previous treatment with AEDs prior to enrollment (2) Neurodegenerative disorder (3) Static encephalopathy (4) CNS malformation

Design outcomes

Primary

MeasureTime frame
To compare the efficacy ( by seizure free interval) and side effects of oral Levetiracetam and Sodium Valproate in childhood epilepsy. Timepoint: To compare the efficacy ( by seizure free interval) and side effects of oral Levetiracetam and Sodium Valproate in childhood epilepsy on 15th day ,1 month , 3 month and 6 month

Secondary

MeasureTime frame
To Analyze other effects of antiepileptics medicationTimepoint: To Analyze other effects of antiepileptics medication on 15th day , 1 month , 3 month & 6 months.

Countries

India

Contacts

Public ContactDR SANJAY MANDOT

Geetanjali Medical College and Hospital

drmandot@yahoo.com9462022900

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026