Comparison of two drugs at surgical site infiltration in patients undergoing lumbar spine surgery

Comparison of Analgesic effect of Bupivacaine with Magnesium Sulfate versus Ropivacaine with Magnesium Sulfate in Surgical Site Infiltration Patient Undergoing Elective Lumbar Spine Surgery under General Anaesthesia A prospective randomized double blind interventional study in department of Anaesthesia at S.M.S. medical college and hospital Jaipur during year 2021-2024. - NIL

Status

Active, not recruiting

Phases

Phase 2Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2023/12/060677

Enrollment

Registered

2023-12-22

Start date

Unknown

Completion date

Unknown

Last updated

2024-01-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Incision site Infiltration: Comparison of Analgesic effect of Bupivacaine with Magnesium Sulfate versus Ropivacaine with Magnesium Sulfate in Surgical Site Infilteration in Patient Unde

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patients willing to give written informed consent. 2. Patient undergoing Lumbar spine surgery. Patients of either gender with age group ranging from 25 to 60 years. 3. ASA grade I and II.

Exclusion criteria

Exclusion criteria: 1. History of seizure, severe systemic disease, mental illness, renal dysfunction, , history of peptic ulcer disease and antacid therapy, coagulopathy, and drug abuse. 2. History of allergy to any of the drugs used during the study. 3. BMI > 35 kg/m2

Design outcomes

Primary

Measure	Time frame
1. Mean VAS score. 2. Mean duration of post operative analgesia. 3. Mean number & total doses of rescue analgesia required in 24hours. 4. Mean post operative hemodynamic parameters (HR, SBP, DBP, MBP). Timepoint: 0 HOUR 6 HOUR 12 HOUR 24 HOUR	—

Secondary

Measure	Time frame
Proportion of cases with side effects. Timepoint: 24 HOURS	—

Countries

India

Contacts

Public ContactDr Bhagy Shree Ganoliya

SMS medical college and attached hospitals

purohit.shobha@gmail.com7737050823

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026