Effectiveness of Adjuvant Homoeopathy in Management of HIV

Effectiveness of Adjuvant Homoeopathy in Management of HIV: a Randomized, Double-blind, Parallel Arm, Placebo-controlled Trial - NIL

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2023/12/060660

Enrollment

500

Registered

2023-12-21

Start date

Unknown

Completion date

Unknown

Last updated

2024-01-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: B20- Human immunodeficiency virus [HIV]disease

Interventions

Intervention1: Homoeopathic Medicine - Crotalus horridus, Anti-retroviral treatment.: Potency of Crotalus horridus will be determined after due consideration of the susceptibility of the participant,

Eligibility

Inclusion criteria

Inclusion criteria: 1. Diagnosed case of HIV infection as per National AIDS Control Programme (NACP-IV) guidelines 2. Undergoing ART 3. Written informed consent

Exclusion criteria

Exclusion criteria: Severe Co-morbidities like - Pneumocystis (jiroveci) Pneumonia, active Mycobacterium Tuberculosis, VDRL Reactive, Hepatitis B positive, Hepatitis C positive and cancers.

Design outcomes

Primary

Measure	Time frame
CD4+ cell count and HIV viral loadTimepoint: Baseline, 6th, 12th, 18th & 24th month	—

Secondary

Measure	Time frame
Biochemical & metabolic parameters – CBC, FBS, HbA1C, BT, CT, PT, PTT, D-dimer LFT, KFT & Fasting Lipid ProfileTimepoint: Baseline, 6th, 12th, 18th, 24th month;Duration of sustained viral suppression.Timepoint: Baseline, 6th, 12th, 18th, 24th month;Symptom management of HIV on SSC-HIV rev scaleTimepoint: Baseline, every 2 months till 2 years;Time to reach CD4+ cell count of 500 cells/µlTimepoint: Baseline, 6th, 12th, 18th, 24th month;Time to reach virological suppression (HIV viral load < 1000 copies/ ml)Timepoint: Baseline, 6th, 12th, 18th, 24th month;WHO-Quality of Life (WHOQOL-HIV BREF)Timepoint: Baseline, every month till 2 years	—

Measure

Time frame

Biochemical & metabolic parameters – CBC, FBS, HbA1C, BT, CT, PT, PTT, D-dimer LFT, KFT & Fasting Lipid ProfileTimepoint: Baseline, 6th, 12th, 18th, 24th month;Duration of sustained viral suppression.Timepoint: Baseline, 6th, 12th, 18th, 24th month;Symptom management of HIV on SSC-HIV rev scaleTimepoint: Baseline, every 2 months till 2 years;Time to reach CD4+ cell count of 500 cells/µlTimepoint: Baseline, 6th, 12th, 18th, 24th month;Time to reach virological suppression (HIV viral load < 1000 copies/ ml)Timepoint: Baseline, 6th, 12th, 18th, 24th month;WHO-Quality of Life (WHOQOL-HIV BREF)Timepoint: Baseline, every month till 2 years

—

Countries

India

Contacts

Public ContactDr Ch Srinivas Reddy

Central Council for Research in Homoeopathy

drdnayak@gmail.com01128525388

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026