Health Condition 1: C00-C14- Malignant neoplasms of lip, oral cavity and pharynx
Conditions
Interventions
Intervention1: LOW LEVEL LASER THERAPY: wavelength of 810 nm, 100-mW output power, laser beam area of approximately 1cm2, three times a week, on alternate days. Therapy will be initiated before the fi
Sponsors
SAKSHI BATRA
Eligibility
Inclusion criteria
Inclusion criteria: i. Histologically proven squamous cell carcinoma of head and neck. ii. Patients treated with upfront r?adio- therapy or chemo-radiotherapy with curative intent. iii. Patients of both gender and between 18 years to 70 years of age. iv. Level I and II neck nodes to be part of the radiotherapy portal.
Exclusion criteria
Exclusion criteria: i. Systemic condition with hyposalivation e.g. DM, End stage renal disease etc. ii. Autoimmune diseases such as Sjogren Syndrome by established diagnosis criteria. iii. Infectious diseases iv. Collagen diseases, as were those with incipient tumors (stage T1 or T2) limited to the larynx, as well as those with trismus (reduced mouth opening capacity) due to surgical sequelae. v. Already on xerostomic drugs (antiretroviral medications, antihistamines, anticholinergics, antihypertensives, decongestants, narcotic analgesics, tricyclic antidepressants)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Stimulated and unstimulated whole saliva flow rateTimepoint: baeline 3 week end of RT 3 month of completion of RT | — |
Secondary
| Measure | Time frame |
|---|---|
| 11-item modified Xerostomia Inventory-Dutch questionnaire versionTimepoint: before therapy and end of the therapy | — |
Countries
India
Contacts
Public ContactDR ADIT
BANARAS HINDU UNIVERSITY
Outcome results
None listed