Regular eating of betel leaves beneficial in heart patients

Cardioprotective Effects of Piper Betle in Heart Failure with Reduced Ejection Fraction: A Randomized Clinical Trial - NIL

Status

Active, not recruiting

Phases

Phase 3Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2023/12/060649

Enrollment

Registered

2023-12-21

Start date

Unknown

Completion date

Unknown

Last updated

2026-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: I509- Heart failure, unspecified

Interventions

Intervention1: Fresh Betel Leaves: Fresh Betel leaves Dose:- 3-4 fresh betel leaves (10-15 gms leaves) Duration- 2 months Control Intervention1: NA: NA

Eligibility

Inclusion criteria

Inclusion criteria: Confirmed diagnosis of low ejection fraction by 2 D Echo report, male and female patients of 18-65 years age group.

Exclusion criteria

Exclusion criteria: 1. Chronic Kidney disease (CKD) 2. Intestinal mal absorption disorders like colitis, IBS etc

Design outcomes

Primary

Measure	Time frame
Improvement in ejection fraction by 2 D EchoTimepoint: 2 months	—

Secondary

Measure	Time frame
Improvement in symptoms occurred due to low ejection fractionTimepoint: 2 months	—

Countries

India

Contacts

Public ContactDr Swati Khartode

Vishwaraj Hospital

opd@vrhpune.com9767133699

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Sep 19, 2026