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Antimicrobial primer versus Regular primer to prevent early caries in orthodontically treated patients

Effect of Organoselenium-containing Antimicrobial Primer on Prevention of White Spot Lesions: A Split-mouth, Controlled Clinical Trial - NIL

Status
Active, not recruiting
Phases
Phase 3Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2023/12/060589
Enrollment
40
Registered
2023-12-20
Start date
Unknown
Completion date
Unknown
Last updated
2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K026- Dental caries on smooth surface Health Condition 2: M264- Malocclusion, unspecified

Interventions

Intervention1: Selenium Primer: organoselenium containing antimicrobial primer for one year Control Intervention1: Non-selenium Primer: Transbond primer for one year

Sponsors

Dr Ritu Gupta
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Age group 18 years and above. Patients with malocclusion in the permanent dentition and requiring fixed orthodontic treatment. Good oral hygiene status Full eruption of posterior teeth

Exclusion criteria

Exclusion criteria: Congenitally missing or impacted teeth. Teeth extracted due to caries. Presence of active carious lesion or enamel hypoplasia Previous history of active orthodontic treatment or extractions Patient with growth and developmental anomaly or general diseases History of any cosmetic allergy Heavy restorations; periodontal diseases, abnormal oral conditions, history of smoking Enamel demineralization or fluorosis staining or bleaching or fluoridation. Severe crowding >6 mm or severely rotated teeth (limiting the appearance of buccal surfaces)

Design outcomes

Primary

MeasureTime frame
Reduced formation of White Spot Lesions (WSLs) during fixed orthodontic treatment with organoselenium primerTimepoint: white spot lesions will be assessed every 4 weeks

Secondary

MeasureTime frame
early detection and prevention of white spot lesions in fixed orthodontic treatmentTimepoint: one year

Countries

India

Contacts

Public ContactDr Pavithranand A

Indira Gandhi Institute of Dental Sciences, Pondicherry

pavithranandammayappan@igids.ac.in9443183590

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026