FindTrial
Sign In

Clotting Factor Replacement Therapy And Bone Mineral Density In Children

A Comparative Study To See The Effect Of Type Of Factor Replacement Therapy On Bone Mineral Density In Children With Severe Hemophilia. - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2023/12/060585
Enrollment
36
Registered
2023-12-20
Start date
Unknown
Completion date
Unknown
Last updated
2024-01-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: D66- Hereditary factor VIII deficiency

Interventions

Intervention1: none: none Intervention2: nil: nil Control Intervention1: Bone Mineral Density Z score: DEXA scanning will be done in all participants at baseline and repeated after 6 months.BMD Z scor

Sponsors

Guru Gobind Singh Medical College and Hospital
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: All males fulfilling the following criteria: Severe hemophilia[Factor VIII Levels <1% of normal at diagnosis]

Exclusion criteria

Exclusion criteria: 1.Evidence of chronic liver,lung or renal disease. 2.Evidence of morbid obesity. 3.Evidence of prolonged neurological diseases and cerebral palsy. 4.Viral markers positive[HIV,HBV,HCV] 5.Evidence of hyperparathyroidism,thyrotoxicosis,cushing syndrome. 6.On steroid or antiepileptic medication. 7.Evidence of vitamin D deficiency.

Design outcomes

Primary

MeasureTime frame
BMD Z score pre and post type of therapyTimepoint: BMD Z score pre and post type of therapy before and after 6 months—

Secondary

MeasureTime frame
Annual bleed rate. Target joint bleed rate. Annual joint bleed point.Timepoint: Pre and post therapy after 6 months.—

Countries

India

Contacts

Public ContactDr Varun Kaul

Guru Gobind Singh Medical College and Hospital, Faridkot

drvarunkaul2009@live.in9876569622

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026