Comparison between Fentanyl and Clonidine as an adjuvant to Ropivacaine heavy in spinal anaesthesia in lower abdominal surgeries

A prospective study to access the efficacy of Clonidine and Fentanyl as adjuvants to Hyperbaric Ropivacaine in infra umbilical surgeries performed under spinal anaesthesia - Not Applicable

Status

Active, not recruiting

Phases

Phase 4

Study type

Observational

Source

CTRI

Registry ID

CTRI/2023/12/060570

Enrollment

100

Registered

2023-12-20

Start date

Unknown

Completion date

Unknown

Last updated

2024-01-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Intrathecal fentanyl as adjuvant to hyperbaric ropivacaine in subarachnoid block for elective lower abdominal surgeries: Intrathecal fentanyl 25mcg along with 3.5ml of 0.75% hyperbaric

Eligibility

Inclusion criteria

Inclusion criteria: Inclusion criteria: 1.ASA grade 1&2 2. Age group of 18-60 years 3. Body mass index between 18.5-24 4. Elective lower abdominal surgeries under spinal anaesthesia

Exclusion criteria

Exclusion criteria: 1. Patients with severe cardio- respiratory disease 2. Patients with hepatic and renal disease 3. Patients with neurological disorders 4. Patients with endocrine disorders 5. Subarachnoid block failure 6. Convertion to general anaesthesia 7. Patients with psychiatric problem 8. Any contraindications for spinal anaesthesia 9. Drug allergy to study drug

Design outcomes

Primary

Measure	Time frame
Comparing block characteristics in respect to sensory block, motor block and duration of post operative analgesiaTimepoint: before spinal, after spinal, at 5,10,15,20,25,30,40,50,60,70, 80,90 min after spinal or till completion of surgery and 2hr, 4hr, 10hr, 14hr,18hr, 22hrs, 24 hrs post op	—

Secondary

Measure	Time frame
1. Highest level of sensory block 2. quality of motor block 3. requirement of rescue analgesia 4. hemodynamic parameters like Mean blood pressure, systolic blood pressure, diastolic blood pressure, heart rate, spo2, respiratory rate 5. evaluation of opioid related adverse effects if anyTimepoint: before spinal, after spinal, at 5,10,15,20,25,30,40,50,60,70, 80,90 min after spinal or till completion of surgery & 2hr, 4hr, 10hr, 14hr,18hr, 22hrs, 24 hrs post op	—

Measure

Time frame

1. Highest level of sensory block 2. quality of motor block 3. requirement of rescue analgesia 4. hemodynamic parameters like Mean blood pressure, systolic blood pressure, diastolic blood pressure, heart rate, spo2, respiratory rate 5. evaluation of opioid related adverse effects if anyTimepoint: before spinal, after spinal, at 5,10,15,20,25,30,40,50,60,70, 80,90 min after spinal or till completion of surgery & 2hr, 4hr, 10hr, 14hr,18hr, 22hrs, 24 hrs post op

—

Countries

India

Contacts

Public ContactDr Asim Kumar Maiti

Midnapore Medical College and hospital

maitiasim1603@gmail.com9233304769

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026