Health Condition 1: K038- Other specified diseases of hard tissues of teeth
Conditions
Interventions
Intervention1: 75 grams of distalizing force: levels of bone biomarkers such as Bone alkaline phosphatase ,type I collagen c telopeptide and osteopontin in peri mini-screw crevicular fluid using 75 gr
Sponsors
Dr Eduru Niharika
Eligibility
Inclusion criteria
Inclusion criteria: 1. Subjects requiring fixed mechanotherapy with first premolar extractions with maximum anchorage. 2. Subjects in the age group of 15-30 years, irrespective of gender. 3. Subjects of ASA1, ASA2 of physical status. 4. Subjects with positive informed consent.
Exclusion criteria
Exclusion criteria: 1. Subjects who had previous history of antibiotic therapy within 3 months from the start of study. 2. Subjects who had previous history of anti-inflammatory drugs within a month from the start of Study. 3. Subjects with history of any systemic disease & hormonal imbalance. 4. Subjects with history of drugs altering bone metabolism.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| levels of bone biomarkers such as bone alkaline phosphatase, type 1 collagen c telopeptide and osteopontin during orthodontic tooth movement using two different force levels in class 2 malocclusion individuals during different time intervalsTimepoint: t0-immediately after placing mini-screws t1-24hrs after placing mini-screws | — |
Secondary
| Measure | Time frame |
|---|---|
| levels of bone biomarkers such as bone alkaline phosphatase, type 1 collagen c telopeptide and osteopontin during orthodontic tooth movement using two different force levels in class 2 malocclusion individuals during different time intervalsTimepoint: t2-7days after loading t3-21 days after loading | — |
Countries
India
Contacts
Public ContactDr. Rajalakshmi SJ
Government dental college and research institute , Bangalore
Outcome results
None listed