Health Condition 1: O- Medical and Surgical
Conditions
Interventions
Intervention1: Plasmalyte-crystalloid: Informed /written consent to participate in the study will be taken from the patient/relative.The patient will be fasting 6hrs for solids and 2 hrs for clear flu
Sponsors
Pt BD Sharma University of health sciences,PGIMS,Rohtak
Eligibility
Inclusion criteria
Inclusion criteria: belonging to ASA grade I-II undergoing neurosurgical procedure under general anaesthesia with arterial and central line placement.
Exclusion criteria
Exclusion criteria: any history of- Cardiac illness, Chronic renal disease, Known allergy to any fluid used in the study, Diabetes mellitus, Coagulation disorder, Deranged liver function test, Pregnant female, Refusal to consent
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To assess the variation on CO2 gap with colloids and crystalloids in neurosurgical patientsTimepoint: At the time of incision,2hrs after incisional the time of closure, after 30 mins in PACU/ICU | — |
Secondary
| Measure | Time frame |
|---|---|
| To observe the effect of fluid therapy on-variation in haemodynamic parameters( Heart rate,mean arterial pressure, diastolic pressure,Systolic blood pressure,Oxygen Saturation,urine output )Timepoint: baseline,1st hour,2nd hour,3rd hour,4th hour,5th hour,6th hour,7th hour,PACU/ICU;To assess correlation between CO2 gap and other tissue hypo perfusion markers- lactate and central venous oxygen saturationTimepoint: At the time of incision, 2hrs after incision, at the time of closure, after 30 mins in PACU/ICU | — |
Countries
India
Contacts
Public ContactDr Smita Chettri
Pt B D Sharma post graduate institute of medical sciences
Outcome results
None listed