Comparison of dexmedetomidine mist inhalation to magnesium sulfate in terms of how blood pressure and hear rate responds when a doctor inserts a tube into windpipe and how often the patient gets sore throat after surgery

EFFECT OF NEBULIZATION WITH DEXMEDETOMIDINE VERSUS MAGNESIUM SULPHATE ON HEMODYNAMIC RESPONSE DURING LARYNGOSCOPY AND INTUBATION AND INCIDENCE OF POST OPERATIVE SORE THROAT - nil

Status

Active, not recruiting

Phases

Phase 1

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2023/12/060483

Enrollment

Registered

2023-12-04

Start date

Unknown

Completion date

Unknown

Last updated

2023-12-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: Laryngoscopy and inubation: Laryngoscopy and intubation with endotracheal tube will be done for patients posted for surgery under general anaesthesia Control Intervention1: Nebulization

Eligibility

Inclusion criteria

Inclusion criteria: 1.ASA grade I or II fit patients. 2. Patients aged between 18 and 60 years of age. 3. Patients undergoing surgeries under general anaesthesia. 4. Haemodynamically stable patients with all routine investigations within normal limits and without any comorbidities. 5.Written informed consent from the concerned patient.

Exclusion criteria

Exclusion criteria: 1.Patients who are not willing to participate in the study. 2.Patients with ASA grade III and above physical status. 3.Patients who are aged less than 18 and more than 60 years of age. 4. Patients who are posted for emergency procedures. 5. Patients with known allergy to the study drugs. 6. Patients with difficult intubation. 7. Patients who are obese. 8. Patients who have psychiatric, neurological, neuromuscular or cardiovascular disease or impairment of hepatic or renal function.

Design outcomes

Primary

Measure	Time frame
To observe the attenuation of pressor responses to laryngoscopy and endotracheal intubation with preoperative nebulization with dexmedetomidine and incidence of post operative sore throatTimepoint: Pre intubation, scopy 0 minutes, every 1 minute upto 10 minutes post intubation, after extubation	—

Secondary

Measure	Time frame
To observe the attenuation of pressor responses to laryngoscopy and endotracheal intubation with preoperative nebulization with dexmedetomidine and incidence of post operative sore throatTimepoint: Pre intubation, scopy 0 minutes, every 1 minute upto 10 minutes post intubation, after extubation	—

Countries

India

Contacts

Public ContactDr C M Suryawanshi

Dr. D Y Patil Medical College and Research Centre, Department of Anaesthesiology

Chhayasuryawanshi@gmail.com02067116499

Outcome results