EFFECT OF STANDARD FLUID THERAPY AND GOAL DIRECTED FLUID THERAPY ON EARLY POSTOPERATIVE OUTCOME IN PATIENTS UNDERGOING ELECTIVE COLORECTAL SURGERY A COMPARATIVE STUDY

EFFECT OF STANDARD FLUID THERAPY AND GOAL DIRECTED FLUID THERAPY ON EARLY POSTOPERATIVE OUTCOME IN PATIENTS UNDERGOING ELECTIVE COLORECTAL SURGERY A COMPARATIVE STUDY - NIL

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2023/12/060480

Enrollment

162

Registered

2023-12-04

Start date

Unknown

Completion date

Unknown

Last updated

2024-07-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: C18- Malignant neoplasm of colon Health Condition 2: C189- Malignant neoplasm of colon, unspecified

Interventions

Intervention1: Goal-directed fluid therapy: Patients will receive Goal-directed fluid therapy using SVV and CO monitoring, in the intraoperative period. Control Intervention1: Standard fluid therapy:

Eligibility

Inclusion criteria

Inclusion criteria: The study will be performed on adult patients, aged 18-65 years, with NYHA class 1-3 undergoing elective colorectal surgery under general anaesthesia, will be considered for the study. Other criteria that will be considered for inclusion are body weight: 55 kg -140 kg and serum albumin >2.5 gm/dl. Patients who will give written informed consent to participate in the study.

Exclusion criteria

Exclusion criteria: Exclusion criteria: The following patients will be excluded. I. Patients with Cognitive limitation II. Patients with Ejection fraction III. Patients with active cardiac dysrhythmia (e.g., rate controlled atrial fibrillation) IV. Patients with Pulmonary disease where expected to receive less than 8 ml/kg tidal volumes V. Patients with Sleep apnoea VI. Patients with Renal disease

Design outcomes

Primary

Measure	Time frame
serum lactate level will be measuredTimepoint: at 8-hour time point in the postoperative period	—

Secondary

Measure	Time frame
Serum lactate level measured at 24-hour time point in the postoperative period.Haemodynamic parameters (HR and MAP) at 8-hour and at 24-hour time points in the postoperative period. Any adverse eventsTimepoint: at 24-hour time point in the postoperative period.	—

Countries

India

Contacts

Public ContactDR DEBOJYOTI DAS

INSTITUTE OF POST GRADUATE MEDICAL EDUCATION and RESEARCH, KOLKATA

arpita_laha@yahoo.com9433326667

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026