Skip to content

To compare the effectiveness of different artificial bone particles in the treatment of severe gum-bone disease

Comparative Clinical and Radiographic Evaluation of G-bone™ (Hydroxyapatite) and G-Graft™ (Hydroxyapatite with Collagen) as Bone Graft Material in the Treatment of Intrabony Defects in Chronic Periodontitis Patients – A Randomized Clinical Trial - RCT

Status
Recruiting
Phases
Phase 2Phase 3
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2023/12/060432
Enrollment
40
Registered
2023-12-01
Start date
Unknown
Completion date
Unknown
Last updated
2024-08-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: M858- Other specified disorders of bonedensity and structure

Interventions

Intervention1: G-bone: hydroxyapatite bone graft material Control Intervention1: G-graft: Hyrdoxyapatite with Collagen

Sponsors

Dr Srishty Sharma
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1)Patients in the age group between 30-60 yrs. 2)Patients diagnosed with Chronic Periodontitis. 3)Patients who are non-smokers or do not consume tobacco in any other form. 4)Patients are in good systemic health with no contraindication to periodontal surgery 5) Patients having pocket depths >5mm, intraosseous defects > 3mm and with radiographic evidence of vertical / angular bone loss in the affected sites.

Exclusion criteria

Exclusion criteria: 1) One-walled osseous defects. 2) Patients suffering from any systemic diseases or with a compromised immune system. 3) Patients who had received any type of periodontal therapy for the past 6 months. 4) Patients taking immunosuppressant drugs like corticosteroids. 5) Patients with a known history of allergy to Doxycycline or Chlorhexidine or any other medicine used in the study. 6) Patients showing unacceptable oral hygiene compliance during / after Phase I periodontal therapy. 7) Patients taking any drug known to cause gingival enlargement. 8) Pregnant and/or lactating mothers.

Design outcomes

Primary

MeasureTime frame
1. Plaque Index (P.I.) (Tureskey-Gilmore-Glickman Modification of Quigley Hein) 2. Gingival Index (G.I.) (Loe & Silness, 1963) 3. Probing Pocket Depth (PPD) 4. Clinical Attachment Level (CAL) Timepoint: Baseline, 1 Month, 3 Months, 6 Months

Secondary

MeasureTime frame
Measurement of bone fill from CEJ to the base of the defect using radiovisiography (RVG) with EzDenti imaging softwareTimepoint: Baseline, 1 Month, 3 Months, 6 Months

Countries

India

Contacts

Public ContactDr Srishty Sharma

Nair Hospital Dental College

maladixit25@gmail.com9223340938

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026