To compare values of HbS concentration on High-Performance Liquid Chromatography in Sickle Cell Patients and Patients with Sickle Cell Crisis.

To assess and evaluate HBs concentration in asymptomatic sickle cell patients and patients with sickle cell crisis through HPLC. - Nil

Status

Active, not recruiting

Phases

Phase 2Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2023/11/060347

Enrollment

Registered

2023-11-29

Start date

Unknown

Completion date

Unknown

Last updated

2023-12-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: D570- Hb-SS disease with crisis

Interventions

Intervention1: Therapeutic: To assess and evaluate HbS concentration in Sickle cell patients and patients with Sickle cell crisis on HPLC. Total duration of intervention- Three years Control Intervent

Eligibility

Inclusion criteria

Inclusion criteria: People who have sickle cell illness. Asymptomatic and symptomatic cases were confirmed on Hb electrophoresis. Patients admitted with sickle cell crisis.

Exclusion criteria

Exclusion criteria: Patients with other hematological pathology. Patients with other hemoglobinopathies. Patients with comorbid conditions. Patients under drug therapy.

Design outcomes

Primary

Measure	Time frame
All the results will be calculated using SPSS version 25. Descriptive statistics will be performed on variables.Timepoint: At baseline.	—

Secondary

Measure	Time frame
It will estimate HbS & other Hb variants on HPLC in Sickle cell patients & patients with Sickle cell crisis amongst children & adults.Timepoint: 2 years	—

Countries

India

Contacts

Public ContactShakti Sagar

Datta Meghe Institute of Higher Education and Research

prg835@gmail.com9373101668

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026